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“We’re not doing 30 bets a year”: Vijay Pande on betting small after running $4 billion at a16z

TechCrunch AI Connie Loizos August 29, 2026
“We’re not doing 30 bets a year”: Vijay Pande on betting small after running $4 billion at a16z
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# AI Is About to Transform Medicine—But Only If Companies Share Data A prominent biotech investor who previously managed $4 billion at a major venture firm is now running a smaller AI-focused fund, and he believes the key to AI actually helping medicine won't come from secretive proprietary data—it will come from companies openly sharing information with each other. He also argues that medicine is shifting from simply discovering new drugs to actually engineering them, though expensive clinical trials remain a major hurdle that AI alone can't solve.

Vijay Pande — who left a16z's roughly $4 billion biotech practice last year to start the much smaller, AI-native VZVC — talks about why biology is finally shifting from a "discovery" science to an "engineering" one, why clinical trials are still brutally expensive, and why he thinks open, shared dat

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